News
- June 2023: BCCC-CURE congratulates Prof. Terry Dowd for publishing “Lead induced differences in bone properties in osteocalcin +/+ and -/- female mice” in Bone Reports.
- February 2023: BCCC-CURE congratulates Prof. Ryan Murelli for publishing “Antiviral activity of amide-appended α-hydroxytropolones against herpes simplex virus-1 and -2” in RSC Advances. This work was performed in collaboration with the Morrison lab at Saint Louis University School of Medicine.
- December 2022: BCCC-CURE congratulates Prof. Maria Contel for publishing the mini-review “Promising heterometallic compounds as anticancer agents: Recent studies in vivo” in Current Opinion in Chemical Biology.
- December 2022: BCCC-CURE congratulates Prof. Maria Contel for publishing “Encapsulation of Gold-Based Anticancer Agents in Protease-Degradable Peptide Nanofilaments Enhances Their Potency” in the Journal of the American Chemical Society. This work was performed in collaboration with the group of Rein Ulijn (Advanced Science Research Center/Hunter College
- December 2022: BCCC-CURE congratulates Alex Berkowitz, Ph.D. who successfully defended his doctoral thesis “Synthesis and Analysis of Novel Troponoid-Based Chemical Probes”. Alex carried out his Ph.D. studies at the CUNY Graduate Center under the supervision of Prof. Ryan Murelli (BCCC-CURE, Brooklyn College).
- December 2022: BCCC-CURE congratulates Prof. Aneta Mieszwaska for publishing “Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy” in Bioconjugate Chemistry. This work was featured on the journal cover.
- November 2022: BCCC-CURE congratulates Yaron Marciano, Ph.D. who successfully defended his doctoral thesis “Optimized Peptide Nanomaterials as Delivery Vehicles for Hydrophobic Metal-Based Anticancer Agents”. Yaron carried out his Ph.D. studies at the CUNY Graduate Center under the supervision of Prof. Maria Contel (BCCC-CURE, Brooklyn College) and Dr. Rein Ulijn (CUNY ASRC).
- October 2022: BCCC-CURE welcomes Ignacio León, PHD., Research associate in CEQUINOR (CONICET-UNLP) and Assistant Professor at the Universidad Nacional de La Plata (Argentina) as Fulbright Scholar. Dr. León will perform research for three months in the laboratory of Prof. Maria Contel.
- October 2022: Prof. Jorge Matias Caviglia publishes “Mouse model of NASH that replicates key features of the human disease and progresses to fibrosis stage 3” in Hepatol Commun.
- October 2022: Prof. Jorge Matias Caviglia co-authors “Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis” in Nature.
- August 2022: BCCC-CURE congratulates Prof. Alexander Greer for publishing “Evaluation of Photosensitizer-Containing Superhydrophobic Surfaces for the Antibacterial Treatment of Periodontal Biofilms” J. Photochem. Photobiol. B.
- July 2022: Congratulations to Prof. Alexander Greer who has been awarded an NSF Single Investigator Award, entitled “Mechanistic Organic Photochemistry: Dark Processes and Toxicity Priming.”
- June 2022: BCCC-CURE congratulates Prof. Maria Contel, who has been elected a Vice-Chair of the 2024 Gordon Conference in Metals in Medicine.
- June 2022: BCCC-CURE congratulates Prof. Mara Schvarzstein and Prof. Shaneen Singh for publishing “A combined in silico and in vivo approach to the structure-function annotation of SPD-2 provides mechanistic insight into its functional diversity” in Cell Cycle.
- May 2022: Prof. Jorge Matias Caviglia co-authors “Promotion of Cholangiocarcinoma Growth by Diverse Cancer-associated Fibroblast Subpopulations” in Cancer Cell.
- May 2022: BCCC-CURE congratulates Prof. Alexander Greer for publishing “Probing the Transition State-to-Intermediate Continuum: Mechanistic Distinction Between a Dry vs Wet Perepoxide in the Singlet Oxygen ‘Ene’ Reaction at the Air-Water Interface” Langmuir.
- May 2022: BCCC-CURE congratulates Prof. Shaneen Singh and Prof. Anjana Saxena for publishing “In silico study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions” in Proteins.
- May 2022: BCCC-CURE congratulates Prof. Sheena Philogene, our very own BCCC-CuRE Science Librarian, who successfully defended her Master’s thesis titled “Using GeoSpatial Analysis to Evaluate Relationships Between Cancer Incidence and Social Factors in Brooklyn, NY.
- April 2022: BCCC-CURE congratulates Prof. Alexander Greer for publishing “Computational Evidence for Tunneling and a Hidden Intermediate in the Biosynthesis of Tetrahydrocannabinol” J. Am. Chem. Soc.
- April 2022: Congratulations to Prof. Shaneen Singh who has been awarded a PSC-CUNY grant entitled “An in silico approach to decipher the mechanism of Cdc6 interactions with key interaction partners.”
- April 2022: Congratulations to Prof. Shaneen Singh who has been awarded a Tow Research and Creativity Grant entitled “In silico study predicts a key role of RNA-binding domains 3 and 4 in Nucleolin-miRNA interactions.
- February 2022: Prof. Margrethe Horlyck-Romanovsky of the Department of Health and Nutrition Sciences received a 2022 CUNY Interdisciplinary Research Grant for her proposal of a community-based participatory diabetes prevention program for Black Caribbean communities in New York City. Prof. Horlyck-Romanovsky is a public health nutrition professional who is committed to addressing intra-ethnic health disparities among populations of African descent. The one-year grant provides nearly $40,000 for the project.
- February 2022: BCCC congratulates Prof. Shaneen Singh for publishing “Using large-scale and long-time all-atom simulations to study the aggregation of amphipathic peptides into amyloid-like fibrils” in Journal of Molecular Liquids.
- February 2022: BCCC congratulates Prof. Amy Ikui and Prof. Shaneen Singh for publishing “Cdc6 is sequentially regulated byPP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae.” in Elife.
- November 2021: Prof. Maria Contel publishes ‘Intracellular Localization Studies of the Luminescent Analogue of an Anticancer Ruthenium Iminophosphorane with High Efficacy in a Triple-Negative Breast Cancer Mouse Model’ in Inorganic Chemistry.
- November 2021: Prof. Mariana Torrente publishes “Trichostatin A Relieves Growth Suppression and Restores Histone Acetylation at Specific Sites in a FUS ALS/FTD Yeast Model” in Biochemistry.
- November 2021: Prof. Mariana Torrente publishes “Changes in Histone H3 Acetylation on Lysine 9 Accompany Aβ 1-40 Overexpression in an Alzheimer’s Disease Yeast Model” in Micropub. Biology.
- October 2021. Prof Cheryl Carmichael publishes “Friends, family, and romantic partners: Three critical relationships in older women’s lives.” Published in Journal of Women & Aging.
- October 2021: Prof. Jorge Matias Caviglia (PI), Prof. Peter Lipke (OSC), and Prof. Juergen Polle (OSC) received an NIH-NIDDK Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15) to study the function of ABHD5 and its role in triacylglycerol lipolysis, with a research group formed mainly by undergraduate students.
- October 2021: US Patent 11,141,490 ‘Antibody Drug Conjugates Based on Gold Compounds’ by Prof. Maria Contel and Dr. Jason Lewis (Memorial Sloan Kettering Cancer Center) and co-workers issued on 10/12/2021.
- October 2021: Prof. Maria Contel publishes ‘Self-Complementary Zwitterionic Peptides Direct Nanoparticle Assembly and Enable Enzymatic Selection of Endocytic Pathways’ in Adv. Mater. Prof. Contel contributed to work lead by Dr. Rein V. Ulijn from our partner institution CUNY Advanced Science Research Center.
- September 2021: BCCC congratulates Prof. Shaneen Singh for publishing “Proteomic Tools for the Analysis of Cytoskeleton Proteins” in Methods Mol Biol.
- September 2021: Prof. Laura J. Juszczak publishes “Clock It: Solving the 3-D Chirality Problem with a 2-D Method-A Simple Algorithm for Teaching and Determining Enantiomers in General Chemistry.” in J. Chem. Ed.
- August 2021: Prof. Alexander Greer publishes “How Tryptophan Oxidation Arises by ‘Dark’ Photoreactions from Chemiexcited Triplet Acetone” in Photochem. Photobiol.
- August 2021: Prof. Anjana Saxena published “Fungi, host immune response, and tumorigenesis” in Am J Physiol Gastrointest Liver Physiol.
- July 2021: BCCC-CURE congratulates Prof. Mim Lal Nakarmi, physics, (PI) and Prof. Laura Juszczak, chemistry (co-PI) who have been awarded an NSF 18-513 Major Research Instrumentation Award for a streak camera to greatly expand the time resolution of fluorescence lifetime measurements for an existing laser-based system.
- July 2021: BCCC-CURE congratulates Prof. Ryan Murelli who was awarded the 2021 Graduate Center Award for Excellence in Mentoring. This award recognizes his commitment to students in the Ph.D. program in Chemistry, many of whom have carried out and continue to carry out research in his lab at Brooklyn College. You can read more about Ryan and the other winners of the award here.
- July 2021: Prof. Maria Contel published “Investigation of the effects and mechanisms of anticancer action of a Ru(II)-arene iminophosphorane compound in triple-negative breast cancer cells” in ChemMedChem.
- July 2021: BCCC-CURE congratulates Prof. Mariana Torrente who was selected to participate in the prestigious American Chemical Society Chem Bio Connections 2021 Summer Seminar Series. Prof. Torrente presented a seminar entitled “A Missing Piece of the Puzzle: Aberrant Histone Modification Landscapes in Neurodegenerative Disease.”
- June 2021: The BCCC-CURE congratulates doctoral student Mina Poursharifi, who successfully defended her Ph.D. thesis, “Synthesis, characterization and applications of peptide-coated nanoparticles,” today. Mina performed her doctoral research under the supervision of Prof. Aneta Mieszwaska.
- June 2021: BCCC-CURE congratulates doctoral student Marek Wlodarczyk, who successfully defended his Ph.D. thesis, “Enhanced Platinum (II) drug delivery for anti-cancer therapy,” today. Marek did his doctoral studies under the supervision of Prof. Aneta Mieszwaska.
- June 2021: BCCC-CURE congratulates Prof. Maria Contel who, in collaboration with Professor Karen Hubbard (City College of New York), has been awarded a PSC-CUNY Enhanced grant (Cycle 52) entitled “Ruthenium-Based Small Molecules as Efficient, less Toxic, and Cost-Effective Chemotherapeutic Options Against Triple Negative Breast Cancer.”
- June 2021: The Brooklyn College Department of Chemistry’s efforts in diversity, equity and inclusion are recognized with the Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences by the American Chemical Society Committee on Minority Affairs.
- June 2021: Prof. Brian Gibney is being honored with the 2020 E. Ann Nalley Regional Award for Volunteer Service to the American Chemical Society.
- May 2021: BCCC-CURE congratulates Ph.D. student Sarah Belh who defended her Ph.D. thesis, titled “Photosensitization and Analytical Study on Reactive Oxygen Intermediates: Self-sorting Surface Radicals and ‘On-off’ Sensitizer Function Mechanisms.” Sarah carried out her Ph.D. studies in the group of Alexander Greer.
- May 2021: Prof. Mariana Torrente was selected to the 2021/2022 Cohort of the Accomplishing Career Transitions Program from the American Society for Cell Biology.
- May 2021: Congratulations to Prof. Mariana Torrente who has been awarded a PSC-CUNY Enhanced grant (Cycle 52) entitled “Delineating the Role of Histone H3 S10 Phosphorylation in C9orf72 ALS.”
- May 2021: Congratulations to Prof. Maria Contel who, in collaboration with Prof. Karen Hubbard (from the City College of New York), has been awarded a PSC-CUNY Enhanced grant (Cycle 52) entitled “Ruthenium-Based Small Molecules as Efficient, less Toxic, and Cost-Effective Chemotherapeutic Options Against Triple Negative Breast Cancer.”
- April 2021: Prof. Maria Contel published “Exploring the Potential of Metallodrugs as Chemotherapeutics for Triple Negative Breast Cancer” in Chemistry A European Journal.
- April 2021: Prof. Maria Contel delivered a Keynote Lecture at the VII Latin-American Meeting on Biological Inorganic Chemistry titled “ Unconventional Metal-Based Drugs as Potential Therapeutic Treatments for Breast Cancer.
- April 2021: Congratulations to Prof. Shaneen Singh who has been awarded a PSC-CUNY Grant entitled “Building a Nek10 interactome: A cancer-focused computational approach to map Nek10’s interacting protein partners.”
- February 2021: Prof. Ryan Murelli publishes “Investigations into a Stoichiometrically Equivalent Intermolecular Oxidopyrylium [5 + 2] Cycloaddition Reaction Leveraging 3-Hydroxy-4-pyrone-Based Oxidopyrylium Dimers” in the Journal of Organic Chemistry.
- December 2020: Prof. Peter Lipke publishes “Through the Back Door: Unconventional Protein Secretion” in The Cell Surface.
- November 2020: Prof. Anjana Saxena publishes “Nucleolin Regulates 14-3-3ζ mRNA and Promotes Cofilin Phosphorylation to Induce Tunneling Nanotube Formation” in The FASEB Journal.
- October 2020: Prof. Guillermo Gerona-Navarro publishes “An Allosteric Modulator of PRC2 Methyltransferase Activity Inhibits Renal Cancer Cell Proliferation” in European Journal of Cancer.
- August 2020: Prof. Anjana Saxena published “Targeting Piezo1 Unleashes Innate Immunity Against Cancer and Infectious Disease” in Science Immunology.
- July 2020: Prof. Alec Greer publishes “Fatty Acid Conjugates of Toluidine Blue O as Amphiphilic Photosensitizers: Synthesis, Solubility, Photophysics and Photochemical Properties†” in Photochemistry and Photobiology
- June 2020: Congratulations to Prof. Ryan Murelli who has received a generous award from the National Institutes of Health for the project “Development and Exploitation of New Synthetic Strategies for Tropolones.” This grant will fund up to $1.54 million to his lab and Brooklyn College over the next four years to advance the synthesis of tropolones and develop tools and knowledge to establish tropolones as anti-viral therapeutics.
- May 2020: Prof. Alec Greer publishes “Adjuvants That Empower the Action of Photodynamic Therapy” in Photochemistry and Photobiology.
- May 2020: Prof. Maria Contel publishes “Auranofin-Based Analogues Are Effective Against Clear Cell Renal Carcinoma In Vivo and Display No Significant Systemic Toxicity” in ACS Pharmacology and Translational Science.
- May 2020: BCCC-CURE congratulates Prof. Terry Dowd, for publishing “An osteocalcin-deficient mouse strain without endocrine abnormalities “ in PLOS Genetics. In collaboration with the Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan.
- April 2020: Prof. Emilio Gallicchio publishes“Combining Alchemical Transformation with a Physical Pathway to Accelerate Absolute Binding Free Energy Calculations of Charged Ligands to Enclosed Binding Sites” in Journal of Chemical Theory and Computation
- April 2020: Prof. Alexander Greer publishes with Professor Joel Liebman ’67 (now at the University of Maryland, Baltimore County) “Why are the elemental nonmetals (F2, Cl2, Br2, I2, S8, P4) of so many hues or of any hues and where is the chromophore? Insight into intera‐X–X bonds” in Photochemistry and Photobiology.
- April 2020: Prof. Maria Contel publishes “SEC hyphenated to a multielement-specific detector unravels the degradation pathway of a bimetallic anticancer complex in human plasma” in the Journal of Chromatography B.
- April 2020: Prof. Ryan Murelli and Assistant Prof. Emilio Gallicchio publish “Amide-containing α-hydroxytropolones as inhibitors of hepatitis B virus replication” in Antiviral Research.
- March 2020: Prof. Alec Greer publishes“In Vivo Tissue Evaluation Reveals Improvements in Explicit PDT Dosimetry” in Photochemistry and Photobiology.
- March 2020: Prof. Ryan Murelli publishes“In Silico Design and Molecular Basis for the Selectivity of Olinone toward the First over the Second Bromodomain of BRD4” in Proteins: Structure, Function, and Bioinformatics
- March 2020: BCCC-CURE congratulates Prof. Cheril Carmichael, PI, who received a National Science Foundation CAREER Award of $896,346. Modeling responsive relationship behavior: Channels of communication, social benefits, and mechanisms of action.
- March 2020: The BCCC-CURE congratulates Prof. Guillermo Gerona-Navarro, who has received a $1.57M award from the National Institutes of Health’s National Institute of General Medical Sciences for the project “Allosteric Modulators of Polycomb Repressive 2 Gene Repression as Potential Therapeutics for the Development of Novel Epigenetic Cancer Therapies.” Part of the projects will be performed in collaboration with Weill Medical College of Cornell University (Professor Ari Melnick.)
- March 2020: Prof. Andres Durantini, a Fulbright Scholar in the Greer laboratory from Sept. 2019 – Nov. 2019, from CONICET and the Universidad Nacional de Río Cuarto, Argentina, collaborated in publishing “Superhydrophobic Surfaces as a Source of Airborne Singlet Oxygen Through Free Space for Photodynamic Therapy” in ACS Appl. Bio Mater.
- March 2020: Assistant Prof. Emilio Gallicchio receives the American Chemical Society COMP OpenEye Outstanding Junior Faculty Award.
- January 2020: Prof. Ryan Murelli publishes “Synthesis of Aryl-Substituted 2-Methoxyphenol Derivatives from Maltol-Derived Oxidopyrylium Cycloadducts through an Acid-Mediated Ring Contraction Cascade” in Chemical Communications.
- January 2020: Prof. Alec Greer in collaboration with Prof. Sherri McFarland published “Synthesis and Characterization of Ru(II) Complexes with π-Expansive Imidazophen Ligands for the Photokilling of Human Melanoma Cells” in Photochem. Photobiol.