At BCCC-CURE research in the area of drug development and delivery is focused on the rational synthesis, characterization and biological evaluation of novel molecules (small organic molecules, metal-based drugs, and peptides) with potential as cancer chemo- and targeted- therapeutics and as theranostics (combining diagnosis and therapy).
Our research includes the use of nanotechnology (nanocarriers based on nanoparticles, polymers, peptides, aptamers and antibodies) to improve the delivery and selectivity of traditional and novel chemotherapeutics with the goal of minimizing toxicity to healthy organs and undesired clinical side effects.
Another topic of interest is the development of photodynamic therapies. In the search for new therapies and delivery methods, we embrace multiple technologies, even engineering. BCCC-CURE researchers work on developing fiber optic-guided drug delivery methods. The study and understanding of the efficacy and mode of action of the new therapeutics is crucial for their implementation and thus, BCCC-CURE researchers work closely with cancer biologists and pharmacologists.
We aim to collaborate with oncologists to translate these findings into treatments to be used in the clinic.