Professor, Biology Department, Brooklyn College, The City University of New York
Ph.D. (Pharmacology) Albert Einstein College of Medicine 2003
Amy Ikui’s laboratory studies DNA replication and cell division using single cell organisms, Saccharomyces cerevisiae (budding yeast) and Chlamydomonas reinhardtii (green algae), with the goal of understanding the molecular mechanism of cell growth control in eukaryotes.
Schroeder L and Ikui AE. Tryptophan confers resistance to SDS-associated cell membrane stress in Saccharomyces cerevisiae PLOS One (2019) 14 (3): e0199484 doi: 10.1371/journal.pone.0199484
Kono K, Ikui AE. A new cell cycle checkpoint senses plasma membrane/cell wall damage in budding yeast BioEssays. (2017) 39(4) doi: 10.1002/bies.201600210
Kono K, Al-Zain A, Schroeder L, Nakanishi M, Ikui AE. Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint in S. cerevisiae. PNAS (2016) 113(25) 6910-15.
Al-Zain A, Schroeder L, Sheglov A, Ikui AE. Cdc6 degradation requires phospho-degron created by GSK-3 and Cdk1 for SCFCdc4 recognition in S. cerevisiae. MBoC. (2015) 26(14):2609-19.
Ikui AE, Rossio V, Schroeder L, Yoshida S. A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication. PLOS Genetics. (2012) 8(12) e1003099.
Grants over the last 5 years
NIH SC1 GM121242 Ikui (PI) 4/1/2017-3/31/2021